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Bioinorganic Chemistry
Dieter Rehder
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Últimas novedades bioquímica química inorgánica
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A truly student-friendly account of this buoyant area of chemistry Broad, balanced coverage makes it the perfect resource for those encountering the field for the first time , and for those who wish to deepen and to broaden their expertise Places particular emphasis on the biological function of the chemical elements, unifying the fields of chemistry and biology in a coherent way Sidebars discuss the analytical approaches adopted to study bioinorganic systems, helping readers to appreciate the experimental basis of the subject An Online Resource Centre provides additional teaching materials for lecturers Bioinorganic chemistry lies at the interface of inorganic chemistry and biochemistry, and explores the function of inorganic species in living systems - from the iron that helps our red blood cells transport oxygen to our tissues, to the calcium that forms an integral part of our bones.
In his book, Rehder provides a broad overview of this dynamic field, reviewing the key chemical elements that have important biological function, and exploring how the chemistry of these elements is central to the function of biological systems.
With sidebars that both review underlying principles of importance to the subject - including the concepts of magnetism and chirality - and discuss some of the analytical approaches that have enabled us to elucidate the biological role of the chemical elements, Bioinorganic Chemistry is the ideal resource for those discovering the field for the first time, and who need a clear, balanced account of the subject.
Online Resource Centre The Online Resource Centre to accompany Bioinorganic Chemistry features figures from the book in electronic format, for use in lecture slides and other teaching materials. Readership: Undergraduates and beginning graduate students studying biological inorganic chemistry as part of a broader chemistry or biochemistry degree programme. |
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ntroduction 1: Bio-Elements in the Periodic Table 2: Pre-Life and Early Life Forms; extremophiles 3: The Alkaline and Alkaline Earth Metals 3.1: Overview 3.2: Ion Channels 3.3: Sodium and Potassium 3.4: Magnesium 3.5: Calcium 4: Iron: General Features of its Inorganic Chemistry and Biochemistry 4.1: General, and Aqueous Chemistry 4.2: Mobilization, Transport, Delivery, and Mineralization of Iron 5: Oxygen Transport and the Respiratory Chain 5.1: Oxygen and oxygen transport by haemoglobin and myoglobin 5.2: Oxygen transport by hemerythrin and haemocyanin 5.3: The Respiratory Chain 6: Oxidoreductases Based on Iron, Manganese, and Copper 6.1: Ribonucleotide Reductases 6.2: Superoxide dismutases, superoxide Reductases, and peroxidases 6.3: Oxygenases and oxidases 7: Oxo-transfer Proteins Based on Molybdenum, Tungsten, and Vanadium 7.1: Molybdo- and Tungsto-pyranopterins 7.1.1: The Xanthine Oxidase Family 7.1.2: The Sulfite Oxidase Family 7.1.3: The Dimethylsulfoxide (DMSO) Reductase Family 7.2: Vanadate-dependent Haloperoxidases 7.3: Model Chemistry 8: The Sulfur Cycle 8.1: Environmental Sulfur Cycling 8.2: Biogenic Metabolism of Sulfur 9: Nitrogenase and Nitrogen Cycle Enzymes 9.1: Overview and Native Nitrogenase 9.2: Nitrogenase Models and Model Reactions 9.3: Denitrification 9.4: Nitric Oxide 10: The Methane Cycle and Nickel Enzymes 10.1: Introduction 10.2: Methanogenesis 10.3: Biogenic Oxidation of Methane 10.4: Nickel Enzymes not Involved in Methane Metabolism 11: Photosynthesis 11.1: Overview 11.2: The Reaction Pathway 11.3: Modeling Photosynthesis 12: The Biochemistry of Zinc 12.1: An Overview of Zinc 12.2: Zinc Enzymes 12.2.1: Carboanhydrases 12.2.2: Hydrolases 12.2.3: Alcohol Dehydrogenase 12.3: The Role of Zinc in the Transcription of Genes 12.4: Thioneins 13: Metal- and Metalloid-Carbon Bonds 13.1: Organometallic Compounds of Transition Metals 13.2: Carbon Bonds to Main Group Metals and Metalloids 14: Inorganics in Medicine 14.1: Metals and Metalloids: An Introduction 14.2: Dysfunction of Iron and Copper Homeostasis 14.2.1: Iron 14.2.2: Copper 14.3: Metals and Metalloids in Therapy 14.3.1: Historical and General Notes 14.3.2: Treatment of Arthritis with Gold Compounds 14.3.3: Cancer Treatment 14.3.4: Further Metal Based Medications 14.3.5: Radiopharmaceuticals 14.4: Metals and Metalloids in Diagnostic Imaging 14.5: The Toxic and Therapeutic Potential of CO, NO and H2S |
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