ean 9781621005384 temática BIOQUÍMICA año Publicación 2012 idioma INGLÉS editorial NOVA SCIENCE formato CARTONÉ 151,24 €    PEDIR   NOVEDAD

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bioquímica

Assembly and deposition of physiologically generated, amyloidogenic proteins occur in various human diseases, referred to as amyloidoses, through misfolding that is either partial unfolding or partial folding of the proteins. A growing body of evidence suggests that misfolding of a given protein is driven by point mutations or by the presence of environmental factors favourable for amyloidogenesis. In this book, the authors present topical research in the study of the composition, function and pathology of amyloids, including the effect of yeast red pigment on amyloid fibrils in vivo and in vitro; amyloid precursor protein and its relation to Alzheimer’s disease; amyloid precursor protein expression after traumatic brain injury; protein aggregation as a modulatory factor in EPMI and the atomic-resolution structures of prion AGAAAAGA amyloid fibrils.

indíce

The Effect of Yeast Red Pigment on Amyloid Fibrils in Vivo & in Vitro; Amyloid Precursor Protein: Its Signaling Aspect & Alzheimer’s Disease; Study of Amyloid Precursor Protein Expression after Traumatic Brain Injury in the Rat; Mechanism of Neurotoxicity of Amyloid-Beta Peptide & the Protective Effects of Docosahexaenoic Acid; Protein Aggregation as a Modulatory Factor in EPM1; Molecular Dynamics Simulations of Amyloid ? Peptides Containing D-Aspartic Acid Residues; Amyloid, Arises on the Membranes & Acts on the Membranes; Insights into the Aggregation Pathway of?a-Synuclein; A Critical Study of the Isosteres of 10th Cysteine Residue of Transthyretin Induced with Cysteine-S-Sulfonate by Ultra-High Resolution Mass Spectrometry; Atomic-Resolution Structures of Prion AGAAAAGA Amyloid Fibrils; Amyloidosis: Etiology, Pathogenesis & Diagnosis; Serum & Urine Free Light Chain Analysis in Evaluation of Amyloidosis AL & other Monoclonal Gammopathies; Transthyretin Val30Met Familial Amyloid Polyneuropathy in Japan; Amyloid Imaging & Biomarkers in MCI & Alzheimer’s Disease.