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In Silico Toxicology: Principles and Applications
Cronin, Mark T.D.;
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Últimas novedades
química general
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| This book enables the reader to develop new, and use existing, in silico methods to predict the toxicity and fate of chemicals. It takes the theme in a logical sequence leading the user through the retrieval, and assessment of quality, of toxicological data and information, the calculation of descriptors and properties, the basis of statistical techniques for quantitative structure-activity relationships (QSARs), the interpretation and validation of models for regulatory use and the mechanistic basis to modelling as well as chemical grouping approaches and application of the models for risk assessment. The book is relevant to toxicologists and modellers using in silico toxicological approaches to perform risk assessment for regulatory purposes and product development. |
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