The book provides scope and knowledge on advanced techniques and its applications into the modern fields of biotechnology—genomics and proteomics. In this book, different genomics and proteomics technologies and principles are examined. The fundamental knowledge presented in this book opens up an entirely new way of approaching DNA chip technology, DNA array assembly, gene expression analysis, assessing changes in genomic DNA, structure-based functional genomics, protein networks, and so on. Topics in the book include: • Different gene products with a similar role in neuronal defense against oxidative • Gene-gene and gene-environment interactions in genetic epidemiology • Elucidation of proto-oncogene c-abl function with the use of mouse models and the disease model of chronic myeloid leukemia • Next-generation sequencing, microbiome evaluation, molecular microbiology, and their impact on human health • Proteomics and prostate cancer • RNA interference therapeutics • Molecular mechanisms of hepatitis C virus entry • Molecular phylogenetics for elucidation of evolutionary processes from biological data • The impact of transgenic crops on soil quality, microbial diversity, and plant-associated communities. • Biotechnological and genomic approaches for abiotic stress tolerance in crop plants The book will be valuable for biotechnology researchers and bioinformatics professionals and students in all fields of biotechnology and will serve to broaden their knowledge about these newer tools, techniques, innovations, and applications.

Preface Different Gene Products with a Similar Role In Neuronal Defense Against Oxidative Stress–Heme Oxygenase System; Zhi-Gang Jiang and Hossein A. Ghanbari Embracing Complexity: Searching for Gene-Gene and Gene Environment Interactions in Genetic Epidemiology; Alison A. Motsinger and David M. Reif Elucidation of Proto-Oncogene C-Abl Function with the Use of Mouse Models and the Disease Model of Chronic Myeloid Leukemia; Jenny F. L. Chau and Baojie Li A Theory on the Molecular Nature of Post-Zygotic Reproductive Isolation; Francisco Prosdocimi Next Generation Sequencing and Microbiome Evaluation: Molecular Microbiology and Its Impact on Human Health; A. Focà, M. C. Liberto, and N. Marascio Proteomics and Prostate Cancer; Jae-Kyung Myung and Marianne D. Sadar RNA Interference Therapeutics - Past, Present and Future; Jayapal Manikandan, Mahmood Rasool, Muhammad Imran Naseer, Kothandaraman Narasimhan, Laila Abdullah Damiati, Kalemegam Gauthaman, Sami Bahlas, and Peter Natesan Pushparaj Molecular Mechanisms of Hepatitis C Virus Entry–Impact of Host Cell Factors for Initiation of Viral Infection; Mirjam B. Zeisel and Thomas F. Baumert Molecular Phylogenetics: A Tool for Elucidation of Evolutionary Processes from Biological Data; Martina Talianova New Insights into the Role of Protein Prenylation and Processing in Plant Development, Phytohormone Signaling and Secondary Metabolism; Dring N. Crowell Mangomics: Information Systems Supporting Advanced Mango Breeding; David J. Innes, Natalie L. Dillon, Heather E. Smyth, Mirko Karan, Timothy A. Holton, Ian S. E. Bally, and Ralf G. Dietzgen Environmental Genomics: The Impact of Transgenic Crops on Soil Quality, Microbial Diversity and Plant Associated Communities; Jeyabalan Sangeetha, Devarajan Thangadurai, Muniswamy David, Roopa T. Somanath, Abhishek C. Mundaragi, and Digambarappa P. Biradar Recent Advances in Biotechnology and Genomic Approaches for Abiotic Stress Tolerance in Crop Plants; Mirza Hasanuzzaman, Rajib Roychowdhury, Joydip Karmakar, Narottam Dey, Kamrun Nahar, and Masayuki Fujita Molecular and Genomic Approaches for Microbial Remediation of Petroleum Contaminated Soils; Jeyabalan Sangeetha, Devarajan Thangadurai, Muniswamy David, and Jadhav Shrinivas Index