ean 9781439854211 temática BIOLOGÍA año Publicación 2012 idioma INGLÉS editorial TAYLOR AND FRANCIS formato RÚSTICA 47,18 €    PEDIR   NOVEDAD

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biología

Mice have long been recognized as a valuable tool for investigating the genetic and physiological bases of human diseases such as diabetes, infectious disease, cancer, heart disease, and a wide array of neurological disorders. With the advent of transgenic and other genetic engineering technologies, the versatility and usefulness of the mouse as a model in biomedical research has soared. As a result, mouse colonies everywhere are expanding, and scientists who previously focused on other models are turning their attention to the mouse. Revised to reflect advances since the first edition, The Laboratory Mouse, Second Edition continues to be the most accessible reference on the biology and care of the laboratory mouse. This guide presents basic information and common procedures in detail to provide a quick reference source for investigators, technicians, and caretakers in the humane care and use of the mouse in the laboratory setting. Expanded, updated, and now in color, this new edition includes coverage of the biological features, husbandry, management, veterinary care, experimental methodology, and resources applying specifically to the mouse.

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Important Biological Features Introduction Stocks and Strains Nomenclature Behavior Anatomic and Physiologic Features Normative Values Hematology Immunodeficient Mice Wild Mice References Husbandry Housing Barriers and Containment Personal Protective Equipment (PPE) Special Considerations for Immunodeficient Mice Environment Sanitation and Pest Control Nutrition Water Breeding Identification and Record Keeping Transportation References Management Regulatory Agencies and Compliance Institutional Animal Care and Use Committee (IACUC) Occupational Health and Zoonotic Diseases References Clinical Medicine Basic Veterinary Supplies Physical Examination of the Mouse Common Spontaneous and Noninfectious Diseases Common Infectious Diseases Treatment and Supportive Care of Sick Mice Clinical Endpoints Treating Disease on a Colony Basis References Preventive Medicine Receiving Testing of Biological Materials Health Surveillance and Monitoring Disease Prevention through Sanitation References Experimental Methodology Restraint Sampling Methods Compound Administration Phenotyping Anesthesia and Analgesia Euthanasia Necropsy References Resources and Additional Information Organizations Publications Electronic Resources Appendix A: Glossary of Phenotyping Terminology and Tests Appendix B: Suggested Cassette Numbering System and Some Trimming Suggestions Index